BDBM520275 US11130750, Example 9

SMILES CC(C)[C@H]1c2ccc(F)cc2CC[C@@]1(CCN(C)CCC(C)(C)c1nc2ccccc2[nH]1)OC(=O)N1CCOCC1

InChI Key InChIKey=LRGPLTNKGUXPEO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520275   

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandPNGBDBM520275(US11130750, Example 9)
Affinity DataIC50: 2.60E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent