BDBM520644 1-methyl-5-(2,3,5,6-tetrafluoro-3'-((4-methylpiperazin-1-yl)methyl)-[1,1'- biphenyl]-4-yl)-1H-benzo[d][1,2,3]triazole-7-carboxylic acid;::US11147801, Compound 35

SMILES CN1CCN(Cc2cccc(c2)-c2c(F)c(F)c(c(F)c2F)-c2cc(C(O)=O)c3n(C)nnc3c2)CC1

InChI Key InChIKey=FNUTZPNSCOECCA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520644   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM520644(US11147801, Compound 35 | 1-methyl-5-(2,3,5,6-tetr...)
Affinity DataIC50: 1.00E+3nMAssay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent