BDBM520656 US11147877, Compound 6::US11147877, Compound 8

SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@H]34)[C@@H]1CC[C@@H]2c1cc(CO)on1

InChI Key InChIKey=GVDKNWHDTOEIQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 520656   

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandPNGBDBM520656(US11147877, Compound 8 | US11147877, Compound 6)
Affinity DataIC50: 110nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandPNGBDBM520656(US11147877, Compound 8 | US11147877, Compound 6)
Affinity DataIC50: 350nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
US Patent