BDBM521168 N-{3-[3-(4-Chlorophenyl)-5-oxo-1-({1-[3-(trifluoromethyl)pyridin-2-yl]-1H-1,2,4-triazol-3-yl}methyl)-1,5-dihydro-4H-1,2,4-triazol-4-yl]-1,1,1-trifluoropropan-2-yl}-3,3-difluorocyclobutane-1-carboxamide (Racemate)::US11149023, Example 63

SMILES FC(F)(F)C(Cn1c(nn(Cc2ncn(n2)-c2ncccc2C(F)(F)F)c1=O)-c1ccc(Cl)cc1)NC(=O)C1CC(F)(F)C1

InChI Key InChIKey=CSGBQCRJBAYXNV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521168   

TargetVasopressin V1a receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM521168(N-{3-[3-(4-Chlorophenyl)-5-oxo-1-({1-[3-(trifluoro...)
Affinity DataIC50: 0.720nMAssay Description:The identification of agonists and antagonists of the V1a and V2 vasopressin receptors from humans, rats and dogs as well as the quantification of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent

TargetVasopressin V2 receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM521168(N-{3-[3-(4-Chlorophenyl)-5-oxo-1-({1-[3-(trifluoro...)
Affinity DataIC50: 58.8nMAssay Description:The identification of agonists and antagonists of the V1a and V2 vasopressin receptors from humans, rats and dogs as well as the quantification of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent