BDBM521446 N-(1-((3aR, 5r,6aS)-5-((5- Chloro-2- (trifluoromethyl) benzyl)(methyl) amino)octa- hydrocyclopenta [c]pyrrole-2- carbonyl)-1H- pyrazol-3- yl)methane- sulfonamide::US11149037, Example 51

SMILES CN(Cc1cc(Cl)ccc1C(F)(F)F)[C@@H]1C[C@H]2CN(C[C@H]2C1)C(=O)n1ccc(NS(C)(=O)=O)n1

InChI Key InChIKey=JGNAADQDXXLXPI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521446   

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM521446(N-(1-((3aR, 5r,6aS)-5-((5- Chloro-2- (trifluoromet...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or PC3 cell membrane fractions for human assays) (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetFatty-acid amide hydrolase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM521446(N-(1-((3aR, 5r,6aS)-5-((5- Chloro-2- (trifluoromet...)
Affinity DataIC50: 550nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or PC3 cell membrane fractions for human assays) (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent