BDBM521452 1-(3-(((1-(3- Acetamido- 1H-pyrazole- 1-carbonyl)- 4-methyl- piperidin-4- yl)(methyl) amino) methyl)-5- (trifluoromethyl) phenyl)cyclo- pentane-1-::US11149037, Example 132

SMILES CN(Cc1cc(cc(c1)C1(CCCC1)C(O)=O)C(F)(F)F)C1(C)CCN(CC1)C(=O)n1ccc(NC(C)=O)n1

InChI Key InChIKey=DBURCSSBBMTPJR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521452   

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM521452(1-(3-(((1-(3- Acetamido- 1H-pyrazole- 1-carbonyl)-...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or PC3 cell membrane fractions for human assays) (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetFatty-acid amide hydrolase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM521452(1-(3-(((1-(3- Acetamido- 1H-pyrazole- 1-carbonyl)-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or PC3 cell membrane fractions for human assays) (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent