BDBM521490 US11149040, Example 20.0

SMILES COC[C@@H]1COc2cc(F)c(F)nc2-c2nnc(NS(=O)(=O)[C@@H](C)[C@@H](OC(C)C)c3ncc(C)cn3)n12

InChI Key InChIKey=QQVHRFKQHMXDGD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 521490   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM521490(US11149040, Example 20.0)
Affinity DataEC50:  990nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent