BDBM521518 US11149040, Example 49.0

SMILES CC(C)O[C@H]([C@H](C)S(=O)(=O)Nc1nnc2CC\C=C/c3cccc(F)c3-n12)c1ncc(C)cn1

InChI Key InChIKey=HIRXZHBRGAQDAD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 521518   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM521518(US11149040, Example 49.0)
Affinity DataEC50:  98nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent