BDBM521523 US11149040, Example 56.0::US11149040, Example 63.0::US11149040, Example 64.0

SMILES CO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc2-c3cccnc3OC[C@@H](COC(C)C)n12)c1ncc(C)cn1

InChI Key InChIKey=WBANJWMQLGKMMU-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 521523   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM521523(US11149040, Example 64.0 | US11149040, Example 63....)
Affinity DataEC50:  2.20E+3nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM521523(US11149040, Example 64.0 | US11149040, Example 63....)
Affinity DataEC50:  800nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM521523(US11149040, Example 64.0 | US11149040, Example 63....)
Affinity DataEC50:  640nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent