BDBM521823 US11155544, Compound 53

SMILES CC1(CCOCC1)C=C(C#N)C(=O)N1CCC[C@H](C1)c1nc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)nccn12

InChI Key InChIKey=NVJMMOUBONIUOV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 521823   

TargetTyrosine-protein kinase BTK(Human)
Principia Biopharma

US Patent
LigandPNGBDBM521823(US11155544, Compound 53)
Affinity DataIC50: 2nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of BTK kinase activity of a compound of the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent