BDBM521831 US11155544, Compound 63

SMILES CC(C)(C=C(C#N)C(=O)N1CCC[C@H](C1)c1nc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)nccn12)N1CCN2[C@H](CCC2=O)C1

InChI Key InChIKey=GFRTWYJLUKCPAD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 521831   

TargetTyrosine-protein kinase BTK(Human)
Principia Biopharma

US Patent
LigandPNGBDBM521831(US11155544, Compound 63)
Affinity DataIC50: 0.900nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of BTK kinase activity of a compound of the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent