BDBM522131 US11160797, Example 39

SMILES CC(C)n1cc(ccc1=O)-c1cncc(c1)-c1ccc2N(C)C(=O)CCCc2c1

InChI Key InChIKey=FYPPBYUPMODRPA-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 522131   

TargetActivin receptor type-1 [172-499,R206H](Human)
Novartis

US Patent
LigandPNGBDBM522131(US11160797, Example 39)
Affinity DataIC50: 60nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetActivin receptor type-1 [172-499](Human)
Novartis

US Patent
LigandPNGBDBM522131(US11160797, Example 39)
Affinity DataIC50: 70nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetActivin receptor type-1 [172-499](Human)
Novartis

US Patent
LigandPNGBDBM522131(US11160797, Example 39)
Affinity DataIC50: 89nMAssay Description:Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

LigandPNGBDBM522131(US11160797, Example 39)
Affinity DataIC50: 350nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

LigandPNGBDBM522131(US11160797, Example 39)
Affinity DataIC50: 390nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

LigandPNGBDBM522131(US11160797, Example 39)
Affinity DataIC50: 400nMAssay Description:Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetTGF-beta receptor type-1 [162-503](Human)
Novartis

US Patent
LigandPNGBDBM522131(US11160797, Example 39)
Affinity DataIC50: 1.40E+3nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent