BDBM522260 US11161839, Example 8e

SMILES COC[C@@H]1CCCN1C(=O)c1cc(Nc2ccc3N(C)C(=C)C=C(NC(C)(C)c4ncccn4)c3c2)c(C#C)c(Cl)n1

InChI Key InChIKey=SKMRNHRIDIAANZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 522260   

TargetB-cell lymphoma 6 protein [5-129](Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM522260(US11161839, Example 8e)
Affinity DataIC50: 28.2nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent