BDBM524042 US11136333, Compound 12a

SMILES Cc1cc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)oc3n2)ccc1F

InChI Key InChIKey=FPTSVINIMZOYRF-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 524042   

TargetTyrosine-protein kinase ABL1(Human)
Texas A&M University System

US Patent
LigandPNGBDBM524042(US11136333, Compound 12a)
Affinity DataKd:  3.5nMAssay Description:This assay is described in https://www.discoverx.com/kinase-data-sheets/abl1-nonphosphorylated.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
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TargetTyrosine-protein kinase ABL1(Human)
Texas A&M University System

US Patent
LigandPNGBDBM524042(US11136333, Compound 12a)
Affinity DataIC50: 17.5nMAssay Description:IC50 against Abelson kinase ABL1 was determined by Life Technologies corporation though the Z′-LITE biochemical assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent