BDBM524440 US11168083, Example 39

SMILES CNC(=O)[C@@H](CCCCNC(N)=N)NC(=O)c1csc(n1)[C@@H]1C[C@@H](O)CN1C(=O)c1cn2cc(Cl)ccc2n1

InChI Key InChIKey=GFAFFEOPNBYDEZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 524440   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM524440(US11168083, Example 39)
Affinity DataEC50:  7.50E+3nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent