BDBM524469 Preparation of 2-ethyl-N-(5-((4-methylpiperazin-1-yl)methyl)pyridin-2-yl)-1-isopropyl-4,5-dihydro-1H-imidazo[4,5-H]quinazolin-8-amine ::US11168088, Compound P-3

SMILES CCN1CCN(Cc2ccc(Nc3ncc4CCc5nc(CC)n(C(C)C)c5-c4n3)nc2)CC1

InChI Key InChIKey=IEBMPMJRZOZFBG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 524469   

LigandPNGBDBM524469(US11168088, Compound P-3 | Preparation of 2-ethyl-...)
Affinity DataIC50: 6nMAssay Description:In the kinase test, a compound to be tested was 1:3 diluted for 8 gradient points, added into a reaction plate, and then added an appropriate amount ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

LigandPNGBDBM524469(US11168088, Compound P-3 | Preparation of 2-ethyl-...)
Affinity DataIC50: 59nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

LigandPNGBDBM524469(US11168088, Compound P-3 | Preparation of 2-ethyl-...)
Affinity DataIC50: 912nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
TBA

US Patent
LigandPNGBDBM524469(US11168088, Compound P-3 | Preparation of 2-ethyl-...)
Affinity DataIC50: 1.15E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent