BDBM524470 Preparation of 8-ethyl-9-isopropyl-N-(5-(piperazin-1-yl)pyridin-2-yl)-6,8-dihydro-5H-pyrazolo[3,4-H]quinazolin-2-amine ::US11168088, Compound P-4

SMILES CCc1nc2CCc3cnc(Nc4ccc(CN5CCNCC5)cn4)nc3-c2n1C(C)C

InChI Key InChIKey=XXGUKQUYYJZJTQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 524470   

LigandPNGBDBM524470(US11168088, Compound P-4 | Preparation of 8-ethyl-...)
Affinity DataIC50: 5nMAssay Description:In the kinase test, a compound to be tested was 1:3 diluted for 8 gradient points, added into a reaction plate, and then added an appropriate amount ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

LigandPNGBDBM524470(US11168088, Compound P-4 | Preparation of 8-ethyl-...)
Affinity DataIC50: 33nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
TBA

US Patent
LigandPNGBDBM524470(US11168088, Compound P-4 | Preparation of 8-ethyl-...)
Affinity DataIC50: 4.76E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

LigandPNGBDBM524470(US11168088, Compound P-4 | Preparation of 8-ethyl-...)
Affinity DataIC50: 7.96E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent