BDBM524474 Preparation of 1-cyclopentyl-N-(5-(piperazin-1-yl)pyridin-2-yl)-4,5-dihydro-1H-pyrazolo[4,3H]quinazolin-8-amine ::US11168088, Compound P-9

SMILES C1CCC(C1)n1ncc2CCc3cnc(Nc4ccc(cn4)N4CCCCC4)nc3-c12

InChI Key InChIKey=YZFXDLSBHMYGKV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 524474   

LigandPNGBDBM524474(US11168088, Compound P-9 | Preparation of 1-cyclop...)
Affinity DataIC50: 8nMAssay Description:In the kinase test, a compound to be tested was 1:3 diluted for 8 gradient points, added into a reaction plate, and then added an appropriate amount ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

LigandPNGBDBM524474(US11168088, Compound P-9 | Preparation of 1-cyclop...)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
TBA

US Patent
LigandPNGBDBM524474(US11168088, Compound P-9 | Preparation of 1-cyclop...)
Affinity DataIC50: 1.44E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

LigandPNGBDBM524474(US11168088, Compound P-9 | Preparation of 1-cyclop...)
Affinity DataIC50: 5.17E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent