BDBM525142 US11168102, Example 24.

SMILES CN=S1(=O)CCC(=CC1)c1cc2c(N[C@H](C)c3cccc(C(F)F)c3F)ncnc2n(C)c1=O

InChI Key InChIKey=ZSKYYAGDAUQXDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 525142   

TargetSon of sevenless homolog 1 [564-1049](Human)
Revolution Medicines

US Patent
LigandPNGBDBM525142(US11168102, Example 24.)
Affinity DataIC50: 13.5nMAssay Description:Using a GE Biacore 8K SPR instrument, avi-tagged SOS1 catalytic domain protein was immobilized to a level of approximately 6000 response units (RU) o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent