BDBM526939 N-(4-fluorophenyl)-5-(3-(6-methylpyridin-3- yl)imidazo[1,2-a]pyridin-8-yl)-2- (trifluoromethyl)benzamide::US11186579, Example 4

SMILES Cc1ccc(cn1)-c1cnc2c(cccn12)-c1ccc(c(c1)C(=O)Nc1ccc(F)cc1)C(F)(F)F

InChI Key InChIKey=QZVZQYMAMVUDAY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 526939   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM526939(N-(4-fluorophenyl)-5-(3-(6-methylpyridin-3- yl)imi...)
Affinity DataEC50:  2.23E+3nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent