BDBM526941 N-(4-fluorophenyl)-5-(3-(pyridin-4- yl)imidazo[1,2-a]pyridin-8-yl)-2- (trifluoromethyl)benzamide::US11186579, Example 6

SMILES Fc1ccc(NC(=O)c2cc(ccc2C(F)(F)F)-c2cccn3c(cnc23)-c2ccncc2)cc1

InChI Key InChIKey=IAVWSSDINIDSJU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 526941   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM526941(N-(4-fluorophenyl)-5-(3-(pyridin-4- yl)imidazo[1,2...)
Affinity DataEC50:  1.42E+3nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent