BDBM526945 5-(3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin- 7-yl)-N-(4-fluorophenyl)-2-methylnicotinamide::US11186579, Example 10::US11186579, Example 12

SMILES Cc1ncc(cc1C(=O)Nc1ccc(F)cc1)-c1cccn2c(cnc12)-c1cccc(F)c1F

InChI Key InChIKey=ZHZWEGQWUBCHNH-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 526945   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM526945(US11186579, Example 12 | 5-(3-(2,3-difluorophenyl)...)
Affinity DataEC50:  403nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM526945(US11186579, Example 12 | 5-(3-(2,3-difluorophenyl)...)
Affinity DataEC50:  441nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent