BDBM526948 5-(3-(4-cyanopyridin-2-yl)imidazo[1,5-a]pyridin- 8-yl)-N-(4-fluorophenyl)-2- (trifluoromethyl)benzamide::US11186579, Example 13

SMILES Cc1ncc(cc1C(=O)Nc1ccc(F)cc1)-c1ccnn2c(cnc12)-c1cccc(F)c1F

InChI Key InChIKey=OWBWSNIUDNQLIA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 526948   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM526948(5-(3-(4-cyanopyridin-2-yl)imidazo[1,5-a]pyridin- 8...)
Affinity DataEC50:  395nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
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Date in BDB:
4/10/2022
Entry Details
US Patent