BDBM526953 N-(4-fluorophenyl)-5-(2-methyl-3-(pyridin-3- yl)imidazo[1,2-a]pyridin-8-yl)-2- (trifluoromethyl)benzamide::US11186579, Example 18

SMILES Cc1nc2c(cccn2c1-c1cccnc1)-c1ccc(c(c1)C(=O)Nc1ccc(F)cc1)C(F)(F)F

InChI Key InChIKey=PPXDQYBMICENQJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 526953   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM526953(N-(4-fluorophenyl)-5-(2-methyl-3-(pyridin-3- yl)im...)
Affinity DataEC50:  165nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent