BDBM526971 2-(5-(3-(2,3-difluorophenyl)imidazo[1,2- a]pyridin-8-yl)-2-(trifluoromethyl)phenyl)-5- fluoro-1H-benzo[d]imidazole::US11186579, Example 36

SMILES Fc1ccc2[nH]c(nc2c1)-c1cc(ccc1C(F)(F)F)-c1cccn2c(cnc12)-c1cccc(F)c1F

InChI Key InChIKey=PCLMDQGUEYDAIH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 526971   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM526971(2-(5-(3-(2,3-difluorophenyl)imidazo[1,2- a]pyridin...)
Affinity DataEC50:  713nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
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Date in BDB:
4/10/2022
Entry Details
US Patent