BDBM527614 US11186588, Example 89

SMILES COc1ncc(F)cc1CN1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(Cl)cc1

InChI Key InChIKey=GEAHCVDIHAPFQN-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 527614   

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Ayumi Pharmaceutical

US Patent

LigandBDBM527614(US11186588, Example 89)Copy SMILESCopy InChI

Affinity DataIC50: 556nMAssay Description:A549/NF-κB-luc cells (available from Panomics, Cat No. LR0051) were prepared at 375,000 cells/mL in the culture medium. The 375,000 cells/mL A54...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/10/2022
Entry Details
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