BDBM527953 (R) and (S) 4-[(3R)-3-methylmorpholin-4-yl]-6-[2-[3-(trifluoromethoxy)phenyl]pyrrolidin-1-yl]-1H-pyridin-2-one::US11179399, Example 15

SMILES C[C@@H]1COCCN1c1cc([nH]c(=O)c1)N1CCCC1c1cccc(OC(F)(F)F)c1

InChI Key InChIKey=XOMBIBRABUIJDB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 527953   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandPNGBDBM527953((R) and (S) 4-[(3R)-3-methylmorpholin-4-yl]-6-[2-[...)
Affinity DataIC50: 60nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
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Date in BDB:
4/10/2022
Entry Details
US Patent