BDBM528003 (R) and (S) 4-[(3R)-3-methylmorpholin-4-yl]-6-(2-thiazol-2-ylpyrrolidin-1-yl)-1H-pyridin-2-one::US11179399, Example 39

SMILES C[C@@H]1COCCN1c1cc([nH]c(=O)c1)N1CCCC1c1nccs1

InChI Key InChIKey=HYEKDPGQMZZYGZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 528003   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandPNGBDBM528003((R) and (S) 4-[(3R)-3-methylmorpholin-4-yl]-6-(2-t...)
Affinity DataIC50: 50nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandPNGBDBM528003((R) and (S) 4-[(3R)-3-methylmorpholin-4-yl]-6-(2-t...)
Affinity DataIC50: 50nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent