BDBM528638 US11192900, Compound 584::US11192900, Example S-62

SMILES COc1cc(=O)n(C)cc1-c1cc(NC(=O)C=C)ccc1Oc1c(C)cccc1C

InChI Key InChIKey=HYDFUWIUUYTAHZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 528638   

TargetBromodomain-containing protein 4 [353-454](Human)
Nuvation Bio

US Patent
LigandPNGBDBM528638(US11192900, Compound 584 | US11192900, Example S-6...)
Affinity DataIC50: 1nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Nuvation Bio

US Patent
LigandPNGBDBM528638(US11192900, Compound 584 | US11192900, Example S-6...)
Affinity DataIC50: 226nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent