BDBM529456 4-chloro-2-(2-chloro-4-fluorophenoxy)-N-(3-sulfamoylphenyl)benzamide ::US11203571, Compound 8

SMILES NS(=O)(=O)c1cccc(NC(=O)c2ccc(Cl)cc2Oc2ccc(F)cc2Cl)c1

InChI Key InChIKey=CELMMHXFUAUCSW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529456   

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM529456(US11203571, Compound 8 | 4-chloro-2-(2-chloro-4-fl...)
Affinity DataIC50: 10nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent