BDBM529464 5-chloro-2-(4-fluoro-2-::US11203571, Compound 16

SMILES COc1cc(F)ccc1Oc1ccc(Cl)cc1C(=O)Nc1cccc(c1)S(N)(=O)=O

InChI Key InChIKey=JAJFCTHDGXAUTA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529464   

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM529464(US11203571, Compound 16 | 5-chloro-2-(4-fluoro-2-)
Affinity DataIC50: 7nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent