BDBM529475 2-(4-fluoro-2-methoxyphenoxy)-N-(3-::US11203571, Compound 27

SMILES COc1cc(F)ccc1Oc1ccc(cc1C(=O)Nc1cccc(c1)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=WKSDWDNFKSJOOC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529475   

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM529475(US11203571, Compound 27 | 2-(4-fluoro-2-methoxyphe...)
Affinity DataIC50: 6nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent