BDBM529480 N-(3-sulfamoylphenyl)-2-(o-tolyloxy)-5-::US11203571, Compound 32

SMILES Cc1ccccc1Oc1ccc(cc1C(=O)Nc1cccc(c1)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=DXZADLVAEBEKFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529480   

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM529480(US11203571, Compound 32 | N-(3-sulfamoylphenyl)-2-...)
Affinity DataIC50: 8nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent