BDBM529487 N-(3-sulfamoylphenyl)-2-(4-::US11203571, Compound 39

SMILES NS(=O)(=O)c1cccc(NC(=O)c2cc(ccc2Oc2ccc(OC(F)(F)F)cc2)C(F)(F)F)c1

InChI Key InChIKey=JXJAXLUACVOIAQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529487   

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM529487(US11203571, Compound 39 | N-(3-sulfamoylphenyl)-2-...)
Affinity DataIC50: 10nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent