BDBM529502 2-(4-fluoro-2-methoxyphenoxy)-N-(3-sulfamoylphenyl)-4-(trifluoromethoxy)benzamide ::US11203571, Compound 54

SMILES COc1cc(F)ccc1Oc1cc(OC(F)(F)F)ccc1C(=O)Nc1cccc(c1)S(N)(=O)=O

InChI Key InChIKey=TUQSVXNFVBKXJU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529502   

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM529502(US11203571, Compound 54 | 2-(4-fluoro-2-methoxyphe...)
Affinity DataIC50: 5nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent