BDBM529504 2-(2-chloro-4-fluorophenoxy)-N-(3-::US11203571, Compound 56

SMILES NS(=O)(=O)c1cccc(NC(=O)c2ccc(OC(F)(F)F)cc2Oc2ccc(F)cc2Cl)c1

InChI Key InChIKey=RGZJXURZZYFNMU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529504   

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM529504(US11203571, Compound 56 | 2-(2-chloro-4-fluorophen...)
Affinity DataIC50: 4nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent