BDBM529506 2-(4-chloro-2-methylphenoxy)-N-(3-::US11203571, Compound 58

SMILES Cc1cc(Cl)ccc1Oc1cccc(c1C(=O)Nc1cccc(c1)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=WVQBZKIOARIROC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529506   

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM529506(US11203571, Compound 58 | 2-(4-chloro-2-methylphen...)
Affinity DataIC50: 6nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent