BDBM529508 N-(3-sulfamoylphenyl)-2-(4-::US11203571, Compound 60

SMILES NS(=O)(=O)c1cccc(NC(=O)c2c(Oc3ccc(OC(F)(F)F)cc3)cccc2C(F)(F)F)c1

InChI Key InChIKey=SWWLUARLIKKSFP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529508   

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM529508(US11203571, Compound 60 | N-(3-sulfamoylphenyl)-2-...)
Affinity DataIC50: 9nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent