BDBM529524 4,5-dichloro-2-(2,4-dimethoxyphenoxy)-::US11203571, Compound 76

SMILES COc1ccc(Oc2cc(Cl)c(Cl)cc2C(=O)Nc2cccc(c2)S(N)(=O)=O)c(OC)c1

InChI Key InChIKey=ALUKLBVCLDYRTQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529524   

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM529524(US11203571, Compound 76 | 4,5-dichloro-2-(2,4-dime...)
Affinity DataIC50: 3nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
Go to US Patent