BDBM529546 2,4-dichloro-6-(4-chloro-2-::US11203571, Compound 98

SMILES COc1cc(Cl)ccc1Oc1cc(Cl)cc(Cl)c1C(=O)Nc1cccc(c1)S(N)(=O)=O

InChI Key InChIKey=RNZZISMBTWSALT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529546   

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM529546(US11203571, Compound 98 | 2,4-dichloro-6-(4-chloro...)
Affinity DataIC50: 0.800nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
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Date in BDB:
4/29/2022
Entry Details
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