BDBM529547 2,4-dichloro-6-(2-fluoro-4-::US11203571, Compound 99

SMILES COc1ccc(Oc2cc(Cl)cc(Cl)c2C(=O)Nc2cccc(c2)S(N)(=O)=O)c(F)c1

InChI Key InChIKey=UEYZYFUCYKOSPW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 529547   

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM529547(US11203571, Compound 99 | 2,4-dichloro-6-(2-fluoro...)
Affinity DataIC50: 5nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent