BDBM530464 7-Fluoro-8-(2-(2-hydroxypropan-2-yl)-1-methyl-1H-imidazol-4-yl)-1-isopropyl-3- (o-tolyl)-4H-quinolizin-4-one.::WO2022070071, Example 1

SMILES CC(C)c1cc(-c2ccccc2C)c(=O)n2cc(F)c(cc12)-c1cn(C)c(n1)C(C)(C)O

InChI Key InChIKey=CVOLIOCIWPHXPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 530464   

LigandPNGBDBM530464(7-Fluoro-8-(2-(2-hydroxypropan-2-yl)-1-methyl-1H-i...)
Affinity DataIC50: 2.11nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070071