BDBM530465 8-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)-7-fluoro-1- isopropyl-3-(o-tolyl)-4H-quinolizin-4-one.::WO2022070071, Example 3

SMILES CCn1c(CO)nn(-c2cc3c(cc(-c4ccccc4C)c(=O)n3cc2F)C(C)C)c1=O

InChI Key InChIKey=KSYWJZBGGJEQKQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 530465   

LigandPNGBDBM530465(8-(4-Ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-...)
Affinity DataIC50: 1.33nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070071