BDBM531929 US11208403, Example 113::US11208403, Example 6

SMILES COc1ccc(cc1OC)-c1cnc(N)c(c1)-c1ccc(NC(=O)c2cn(CC3CCOCC3)cc(-c3ccc(Br)cc3)c2=O)cc1

InChI Key InChIKey=YLKPPBUPVVBPDB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 531929   

TargetTyrosine-protein kinase receptor UFO(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM531929(US11208403, Example 113 | US11208403, Example 6)
Affinity DataIC50: 1.30nMAssay Description:A kinase dilution solution containing 170 ng/ml AXL (the 464th to 885th amino acids of the intracellular domain of human AXL expressed as a fusion pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM531929(US11208403, Example 113 | US11208403, Example 6)
Affinity DataIC50: 3.60nMAssay Description:A kinase dilution solution containing 170 ng/ml AXL (the 464th to 885th amino acids of the intracellular domain of human AXL expressed as a fusion pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM531929(US11208403, Example 113 | US11208403, Example 6)
Affinity DataIC50: 271nMAssay Description:A kinase dilution solution containing 20 ng/ml Mer (the 528th to 999th amino acids of the intracellular domain of human MER expressed as a fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM531929(US11208403, Example 113 | US11208403, Example 6)
Affinity DataIC50: 1.08E+3nMAssay Description:A kinase dilution solution containing 20 ng/ml Mer (the 528th to 999th amino acids of the intracellular domain of human MER expressed as a fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent