BDBM532013 US11208403, Example 90

SMILES COc1ccc(cc1OC)-c1cnc(N)c(c1)-c1ccc(NC(=O)c2cn(CC3CCOCC3)cc(-c3ccc(C)cc3)c2=O)nc1

InChI Key InChIKey=WFHGEWDDDBUGKR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 532013   

TargetTyrosine-protein kinase receptor UFO(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM532013(US11208403, Example 90)
Affinity DataIC50: 0.600nMAssay Description:A kinase dilution solution containing 170 ng/ml AXL (the 464th to 885th amino acids of the intracellular domain of human AXL expressed as a fusion pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM532013(US11208403, Example 90)
Affinity DataIC50: 11nMAssay Description:A phosphorylated Axl (hereinafter, referred to as pAxl) inhibition test was conducted using a human non-small cell lung cancer-derived cell line NCI-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM532013(US11208403, Example 90)
Affinity DataIC50: 107nMAssay Description:A kinase dilution solution containing 20 ng/ml Mer (the 528th to 999th amino acids of the intracellular domain of human MER expressed as a fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent