BDBM532160 US11208418, Example 7

SMILES OC(=O)c1ccc2CCc3nc(OCc4c(onc4-c4c(Cl)cc(F)cc4Cl)C4CC4)ccc3Oc2c1

InChI Key InChIKey=SWBCSZCFJRRETK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 532160   

TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM532160(US11208418, Example 7)
Affinity DataEC50:  7.40nMAssay Description:Agonist activity at FXR (unknown origin) incubated for 15 mins by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM532160(US11208418, Example 7)
Affinity DataEC50:  7.40nMAssay Description:Purchasing Invitrogen PV4833 Kit.Step 1, the compound was weighed and dissolved in 100% DMSO, the highest concentration is 3000 μM, and then dil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent