BDBM532378 US11214540, Example 36

SMILES [#6]\[#6](-[#6])=[#6]\[#6](-[#6]C([#6])([#6])c1ccc(F)cc1)-[#7]-1-[#6]-[#6]C2([#6]-[#6]-[#8]-[#6]-[#6]2)[#6]-[#6]-1

InChI Key InChIKey=MFABFPQMMHSRKN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 532378   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Cognition Therapeutics

US Patent
LigandPNGBDBM532378(US11214540, Example 36)
Affinity DataKi:  12nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
Go to US Patent

TargetSigma intracellular receptor 2(Rat)
Cognition Therapeutics

US Patent
LigandPNGBDBM532378(US11214540, Example 36)
Affinity DataKi:  40nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
Go to US Patent