BDBM532558 2-[6-[3-Chloro-4-(trifluoromethoxy)phenyl]pyrazolo[3,4-b]pyrazin-1-yl]-::US11214563, Example 19

SMILES CN(C)C(=O)Cn1ncc2ncc(nc12)-c1cc(F)c(C)c(F)c1

InChI Key InChIKey=SWLCJJIINVYLMV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 532558   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM532558(US11214563, Example 19 | 2-[6-[3-Chloro-4-(trifluo...)
Affinity DataIC50: 1.04E+3nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent