BDBM532564 1-(Azetidin-1-yl)-2-[6-[3-(difluoromethyl)-4-fluoro-phenyl]-3-fluoro-::US11214563, Example 25

SMILES CC(F)(F)c1cc(ccc1Cl)-c1cnc2cnn(CC(=O)N3CCC3)c2n1

InChI Key InChIKey=QDLNSDRZLAEEOB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 532564   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM532564(US11214563, Example 25 | 1-(Azetidin-1-yl)-2-[6-[3...)
Affinity DataIC50: 65nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
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Date in BDB:
5/8/2022
Entry Details
US Patent