BDBM532566 1-(Azetidin-1-yl)-2-[6-[3-(1,1-difluoroethyl)-4-fluoro-phenyl]pyrazolo[3,4-::US11214563, Example 27

SMILES FC(F)Oc1cc(ccc1F)-c1cnc2cnn(CC(=O)N3CCC3)c2n1

InChI Key InChIKey=IXRLNMUIQZVMFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 532566   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM532566(US11214563, Example 27 | 1-(Azetidin-1-yl)-2-[6-[3...)
Affinity DataIC50: 126nMAssay Description:Twenty four hours before measurements, the expression of the NMDA receptors in the stable cell line is induced with Tet-On inducible system in the pr...More data for this Ligand-Target Pair
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Date in BDB:
5/8/2022
Entry Details
US Patent